PHYLOGENETIC AND BIOCHEMICAL ANALYSIS OF CALSEQUESTRIN STRUCTURE AND ASSOCIATION OF ITS VARIANTS WITH CARDIAC DISORDERS

Phylogenetic and biochemical analysis of calsequestrin structure and association of its variants with cardiac disorders

Abstract Calsequestrin is among the most abundant proteins in muscle sarcoplasmic Show Your Pride reticulum and displays a high capacity but a low affinity for Ca2+ binding.In mammals, calsequestrin is encoded by two genes, CASQ1 and CASQ2, which are expressed almost exclusively in skeletal and cardiac muscles, respectively.Phylogenetic analysis in

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When Can Repentance Mitigate Criminal Punishment?

In the criminal law literature, repentance becomes relevant in a specific context: conviction, more precisely, in determining the penalty of an individual who has been found responsible for the commission of a crime LAST MEAL CHOCOLATE and who, in turn, expresses remorse for their actions.From a communicative conception of punishment, this paper ad

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